Article
Molecular characterization and genotype distribution of thioester-containing protein 1 gene in Anopheles gambiae mosquitoes in western Kenya.
Malaria journal - 10 Aug 2022
Onyango Shirley A, Ochwedo Kevin O, Machani Maxwell G, Olumeh Julius O, Debrah Isaiah, Omondi Collince J, Ogolla Sidney O, Lee Ming-Chieh, Zhou Guofa, Kokwaro Elizabeth, Kazura James W, Afrane Yaw A, Githeko Andrew K, Zhong Daibin, Yan Guiyun
Abstract excerpt
BACKGROUND: Evolutionary pressures lead to the selection of efficient malaria vectors either resistant or susceptible to Plasmodium parasites. These forces may favour the introduction of species genotypes that adapt to new breeding habitats, potentially having an impact on malaria transmission. Thioester-containing protein 1 (TEP1) of Anopheles gambiae complex plays an important role in innate immune defenses...
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