Article
Genetic predisposition to inflammation: a new risk factor of Alzheimer's disease.
Neuroscience bulletin - 1 Oct 2008
Wan Ying, Wang Gang, Chen Sheng-Di
Abstract excerpt
Inflammation has been shown to play an important role in the progression of Alzheimer's disease (AD). Recent epidemical study indicates that the incidence of AD in some populations is substantially influenced by the gene polymorphisms of the inflammation mediators. Meanwhile, an ensured risk factor, the ApoE epsilon4 allele is also reported to directly promote inflammation. Accordingly, it appears that an...
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