Article
The human leukocyte antigen class III haplotype approach: new insight in Alzheimer's disease inflammation hypothesis.
Current Alzheimer research - 1 Dec 2013
Maggioli Elisa, Boiocchi Chiara, Zorzetto Michele, Sinforiani Elena, Cereda Cristina, Ricevuti Giovanni, Cuccia Mariaclara
Abstract excerpt
The Alzheimer's disease "inflammation hypothesis" has emerged only recently, suggesting the risk of developing AD might be influenced by variants of genes encoding for inflammatory mediators. In order to investigate in this direction, genomic DNA from 194 Italian AD cases and 454 healthy controls matched by gender and ethnicity was analyzed for the Receptor for Advanced Glycation End products (RAGE, HLA class...
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