Article
Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11.
Immunological reviews - 1 Jan 2010
Chang Sook Kyung, Gu Zhizhan, Brenner Michael B
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting the joint synovium. The normal synovium consists of a lining layer of fibroblast-like synoviocytes (FLS) and macrophages, one to three cells deep that overlies the loose connective tissue of the synovial sublining. During the course of RA, the synovium is the site of inflammation where immune cells are massively infiltrated, and the...
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