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Article

HER-2/neu Ile655Val polymorphism and the risk of breast cancer.

Annals of the New York Academy of Sciences - 1 Sept 2008

Siddig Awatif, Mohamed Abdelrahim Osman, Kamal Hammed, Awad Salma, Hassan Ahmed H, Zilahi Erika, Al-Haj Mohammed, Bernsen Roos, Adem Abdu

Abstract excerpt

Genetic alterations of the proto-oncogene human epidermal growth factor receptor (HER-2/neu) have been shown to induce malignant transformation and metastasis. Genotyping studies have addressed the association of codon 655 isoleucine to valine polymorphism located in the transmembrane coding region and the risk of breast cancer, but the results are inconsistent. In this study, we investigated the association of...

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Identifiers

PMID: 18837888
DOI: 10.1196/annals.1414.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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