Article
The erbB2/HER2/neu receptor polymorphism Ile655Val and breast cancer risk.
Pharmacogenetics and genomics - 1 Jul 2005
Cox David G, Hankinson Susan E, Hunter David J
Abstract excerpt
The erbB2 (HER2/neu) gene is found amplified in tumours. A single nucleotide polymorphism at codon 655 (Ile655Val) has been studied in a number of case-control studies with respect to breast cancer risk, with conflicting results. The aim of the present study was to examine the association between this polymorphism and breast cancer risk in a prospective, predominantly Caucasian cohort of women, the Nurses' Health...
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