Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HER-2/neu gene codon 655 (Ile/Val) polymorphism in breast carcinoma patients.

Genetic testing and molecular biomarkers - 1 Mar 2011

Sezgin Ezgi, Sahin Feride Iffet, Yagmurdur Mahmut Can, Demirhan Beyhan

Abstract excerpt

Amplification and/or overexpression of HER-2/neu has been reported to be associated with poor prognosis in breast cancer. One single-nucleotide polymorphism at codon 655 indicates a guanine-to-adenine substitution (Ile655Val) in the transmembrane domain-coding region of the HER-2/neu gene reported to be associated with increased risk of breast cancer. However, several studies have shown that this association is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Case-Control Studies
Share to Codon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, erbB-2

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Receptor, ErbB-2

Share to Risk Factors

Source

Identifiers

PMID: 21204706
DOI: 10.1089/gtmb.2010.0126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HER-2/neu gene codon 655 (Ile/Val) polymorphism in breast carcinoma patients.PMID 21204706Read ↗

The influence of HER2 genotypes as molecular markers on breast cancer outcome.Semantic proximity Read ↗

Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.Semantic proximity Read ↗

HER-2/neu Ile655Val polymorphism and the risk of breast cancer.Semantic proximity Read ↗

Ile to Val polymorphism at codon 655 of HER-2 gene and breast cancer risk in Iranian women.Semantic proximity Read ↗

The influence of serum HER-2 levels and HER-2 codon 655 polymorphism on breast cancer outcome.Semantic proximity Read ↗

HER2 Ile655Val polymorphism contributes to breast cancer risk: evidence from 27 case-control studies.Semantic proximity Read ↗

The erbB2/HER2/neu receptor polymorphism Ile655Val and breast cancer risk.Semantic proximity Read ↗

HER2 codon 655 polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

The rare ERBB2 variant Ile654Val is associated with an increased familial breast cancer risk.Semantic proximity Read ↗

Association of HER2 codon 655 polymorphism with ovarian cancer.Semantic proximity Read ↗

Allelic imbalance of HER-2 codon 655 polymorphism among different religious/ethnic populations of northern Greece and its association with the development and the malignant phenotype of breast cancer.Semantic proximity Read ↗

HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.