Article
T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal?
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2006
Mongkolsapaya Juthathip, Duangchinda Thaneeya, Dejnirattisai Wanwisa, Vasanawathana Sirijit, Avirutnan Panisadee, Jairungsri Aroonroong, Khemnu Nuanpan, Tangthawornchaikul Nattaya, Chotiyarnwong Pojchong, Sae-Jang Kanokwan, Koch Michael, Jones Yvonne, McMichael Andrew, Xu Xiaoning, Malasit Prida, Screaton Gavin
Abstract excerpt
Dengue virus infection poses a growing public health and economic burden in a number of tropical and subtropical countries. Dengue circulates as a number of quasispecies, which can be divided by serology into four groups or serotypes. An interesting feature of Dengue, recognized over five decades ago, is that most severe cases that show hemorrhagic fever are not suffering from a primary infection. Instead, they...
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