Article
Structural model of the Ca V 1.2 pore.
Channels (Austin, Tex.) - 1 Jan 2000
Stary Anna, Shafrir Yinon, Hering Steffen, Wolschann Peter, Guy H Robert
Abstract excerpt
Understanding the structure and functional mechanisms of voltage-gated calcium channels remains a major task in membrane biophysics. In the absence of three dimensional structures, homology modeling techniques are the method of choice, to address questions concerning the structure of these channels. We have developed models of the open Ca(V)1.2 pore, based on the crystal structure of the mammalian voltage-gated...
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