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Article

Models of the structure and gating mechanisms of the pore domain of the NaChBac ion channel.

Biophysical journal - 1 Oct 2008

Shafrir Yinon, Durell Stewart R, Guy H Robert

Abstract excerpt

The NaChBac prokaryotic sodium channel appears to be a descendent of an evolutionary link between voltage-gated K(V) and Ca(V) channels. Like K(V) channels, four identical six-transmembrane subunits comprise the NaChBac channel, but its selectivity filter possesses a signature sequence of eukaryotic Ca(V) channels. We developed structural models of the NaChBac channel in closed and open conformations, using...

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Identifiers

PMID: 18641075
DOI: 10.1529/biophysj.108.135327
PMCID: PMC2553130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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