Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Topology of the Shaker potassium channel probed with hydrophilic epitope insertions.

The Journal of cell biology - 10 Mar 1997

Shih T M, Goldin A L

Abstract excerpt

The structure of the Shaker potassium channel has been modeled as passing through the cellular membrane eight times with both the NH2 and COOH termini on the cytoplasmic side (Durrell, S.R., and H.R. Guy. 1992. Biophys. J. 62:238-250). To test the validity of this model, we have inserted an epitope consisting of eight hydrophilic amino acids (DYKDDDDK) in predicted extracellular and intracellular loops throughout...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Epitopes
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oocytes

Share to Peptides

Share to Potassium Channels

Share to Protein Conformation

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9060468
DOI: 10.1083/jcb.136.5.1037
PMCID: PMC2132486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Topology of the Shaker potassium channel probed with hydrophilic epitope insertions.PMID 9060468Read ↗

Investigating the putative glycine hinge in Shaker potassium channel.Semantic proximity Read ↗

Role of hydrophobic and ionic forces in the movement of S4 of the Shaker potassium channel.Semantic proximity Read ↗

Voltage-dependent structural interactions in the Shaker K(+) channel.Semantic proximity Read ↗

Differences in gating among amino-terminal variants of Shaker potassium channels.Semantic proximity Read ↗

Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits.Semantic proximity Read ↗

Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel.Semantic proximity Read ↗

A characterization of the activating structural rearrangements in voltage-dependent Shaker K+ channels.Semantic proximity Read ↗

Structural model of the outer vestibule and selectivity filter of the Shaker voltage-gated K+ channel.Semantic proximity Read ↗

Characterization of five RNA editing sites in Shab potassium channels.Semantic proximity Read ↗

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects.Semantic proximity Read ↗

Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels.Semantic proximity Read ↗

Potassium channel opening: a subtle two-step.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.