Article
Genetic relationship between anxiety-related and fear-related behaviors in BXD recombinant inbred mice.
Behavioural pharmacology - 1 Mar 2009
Brigman Jonathan L, Mathur Poonam, Lu Lu, Williams Robert W, Holmes Andrew
Abstract excerpt
Mood and anxiety disorders, and rodent phenotypic measures modeling these disorders, have a strong genetic component. Various assays are used to study the neurobiological basis of fear-related and anxiety-related behaviors, phenotype genetically modified mice, and elucidate pharmacological modulation of these behaviors for medication development. Earlier work, however, suggests that different trait measures are...
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