Article
Mapping quantitative trait loci for fear-like behaviors in mice.
Genomics - 15 Nov 1997
Gershenfeld H K, Paul S M
Abstract excerpt
Two mouse models developed for screening anxiolytic drugs were selected for genetic analysis, namely "wall-seeking" tendency in an open field ("thigmotaxis") and the light-to-dark transition (LD) paradigm, a conflict test. These tests measure differences in naturalistic tendencies of mice to explore a novel environment and to avoid a bright light or the center of an open field. In an F2 intercross of two strains...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
