Article
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype.
Genetics - 1 Nov 2006
Nadler Jessica J, Zou Fei, Huang Hanwen, Moy Sheryl S, Lauder Jean, Crawley Jacqueline N, Threadgill David W, Wright Fred A, Magnuson Terry R
Abstract excerpt
Behaviors are often highly heritable, polygenic traits. To investigate molecular mediators of behavior, we analyzed gene expression patterns across seven brain regions (amygdala, basal ganglia, cerebellum, frontal cortex, hippocampus, cingulate cortex, and olfactory bulb) of 10 different inbred mouse strains (129S1/SvImJ, A/J, AKR/J, BALB/cByJ, BTBR T+ tf/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J, and FVB/NJ)....
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