Article
Identification of quantitative trait Loci for anxiety and locomotion phenotypes in rat recombinant inbred strains.
Behavior genetics - 1 Jan 2004
Conti Lisa H, Jirout Martin, Breen Laura, Vanella Jessica J, Schork Nicholas J, Printz Morton P
Abstract excerpt
Anxiety disorders are phenotypically complex and may involve multiple genetic influences on many neurotransmitter systems. Rodent tests used to investigate genetic influences on anxiety-like phenotypes have face and predictive validity as models for anxiety in humans. If multiple genes contribute additively to a trait, the trait will be continuously distributed and be amenable to detection of associations between...
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