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Article

Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits.

Genes, brain, and behavior - 1 Jul 2011

Sokoloff G, Parker C C, Lim J E, Palmer A A

Abstract excerpt

Anxiety, like other psychiatric disorders, is a complex neurobehavioral trait, making identification of causal genes difficult. In this study, we examined anxiety-like behavior and fear conditioning (FC) in an F(2) intercross of C57BL/6J and DBA/2J mice. We identified numerous quantitative trait loci (QTL) influencing anxiety-like behavior in both open field (OF) and FC tests. Many of these QTL were mapped back...

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Share to Anxiety
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Share to Conditioning, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Mice, Inbred DBA

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Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 21554534
DOI: 10.1111/j.1601-183X.2011.00699.x
PMCID: PMC3756832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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