Article
Association of interferon-gamma and tumor necrosis factor alpha polymorphisms with susceptibility to vitiligo in Iranian patients.
Archives of dermatological research - 1 Jan 2009
Namian Ali-Mohammad, Shahbaz Shima, Salmanpoor Rahmatolah, Namazi Mohammad-Reza, Dehghani Farideh, Kamali-Sarvestani Eskandar
Abstract excerpt
Vitiligo is a common skin disorder that is caused by selective destruction of melanocytes, resulting in disfiguring loss of pigment. There are convincing evidences that cytokines and T cell mediated immunity may have a role in its pathogenesis. Given the fact that cytokine production is under genetic control, in this study, we have investigated IFN-gamma +874 T/A and TNF-alpha -308 G/A gene polymorphisms in a...
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