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Article

Tumor necrosis factor-α and -β genetic polymorphisms as a risk factor in Saudi patients with vitiligo.

Genetics and molecular research : GMR - 8 Jul 2013

Al-Harthi F, Zouman A, Arfin M, Tariq M, Al-Asmari A

Abstract excerpt

Vitiligo is an acquired depigmentary disorder of the skin, characterized by multiple susceptibility loci and genetic heterogeneity. The etiology of vitiligo is unknown but several hypotheses, including an autoimmune origin, have been proposed. Tumor necrosis factor (TNF)-α, a pleiotropic proinflammatory cytokine, has been shown to play a critical role in several autoimmune diseases including vitiligo. The aim of...

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PMID: 23884763
DOI: 10.4238/2013.July.8.1

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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