Article
Association analysis of class II cytokine and receptor genes in vitiligo patients.
Human immunology - 1 May 2016
Traks Tanel, Karelson Maire, Reimann Ene, Rätsep Ranno, Silm Helgi, Vasar Eero, Kõks Sulev, Kingo Külli
Abstract excerpt
The loss of melanocytes in vitiligo is mainly attributed to defective autoimmune mechanisms and lately autoinflammatory mediators have become more emphasized. Among these, a number of class II cytokines and their receptors have displayed altered expression patterns in vitiligo. Thus, we selected 30 SNPs from the regions of respective genes to be genotyped in Estonian case-control sample (109 and 328 individuals,...
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