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Association Analysis of Tumor Necrosis Factor Alpha Promoter Polymorphisms and Vitiligo Susceptibility in South Indian Tamils.

Dermatology (Basel, Switzerland) - 1 Jan 2020

Rajendiran Kalai Selvi, Rajappa Medha, Chandrashekar Laxmisha, Thappa Devinder Mohan, Devaraju Panneer

Abstract excerpt

Tumor necrosis factor alpha (TNF-α) has been associated with the pathogenesis of several autoimmune diseases. Also, various studies in different ethnics showed an association between TNF-α gene polymorphisms and susceptibility to vitiligo. The paucity of genetic data led us to undertake this study to evaluate the association of five TNF-α SNPs (rs1799964, rs1800630, rs1799724, rs1800629, and rs361525) with the...

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Share to Genetic Predisposition to Disease
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Share to Polymorphism, Single Nucleotide
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PMID: 32074604
DOI: 10.1159/000505544

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