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Article

Mechanisms of ATII-to-ATI Cell Differentiation during Lung Regeneration

30 Apr 2020

Abstract excerpt

The alveolar epithelium consists of (ATI) and type II (ATII) cells. ATI cells cover the majority of the alveolar surface due to their thin, elongated shape and are largely responsible for barrier function and gas exchange. During lung injury, ATI cells are susceptible to injury, including cell death. Under some circumstances, ATII cells also die. To regenerate lost epithelial cells, ATII cells serve as progenitor...

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PMID: 32366033
DOI: 10.3390/ijms21093188

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