Article
A functional Ser(413)/Ser(413) PAI-2 polymorphism is associated with susceptibility and damage index score in systemic lupus erythematosus.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000
Palafox-Sánchez Claudia A, Vázquez-Del Mercado Mónica, Orozco-Barocio Gerardo, García-De la Torre Ignacio, Torres-Carrillo Norma, Torres-Carrillo Nora M, Illades-Aguiar Berenice, Muñoz-Valle José F
Abstract excerpt
Systemic lupus erythematosus in some cases is characterized for development of thrombotic events with a significantly increased risk of mortality. The frequencies and clinical associations of Ser(413)/Cys(413) PAI-2 polymorphism in 40 systemic lupus erythematosus, 50 rheumatoid arthritis patients, and 100 healthy subjects were investigated. The Ser(413)/Ser(413) genotype frequency was 53% (lupus), 36% (rheumatoid...
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