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Article

Role of MMP-2 and its inhibitor TIMP-2 as biomarkers for susceptibility to systemic lupus erythematosus.

Biomarkers in medicine - 1 Aug 2020

Vira Hemant J, Pradhan Vandana D, Umare Vinod D, Chaudhary Ajay K, Rajadhyksha Anjali G, Nadkar Milind Y, Ghosh Kanjaksha, Nadkarni Anita H

Abstract excerpt

Aim: To investigate the possible association between MMP-2 (-1575 G/A, -1306 C/T) and its inhibitor TIMP-2 (-418 G/C) functional polymorphisms with development of severity in systemic lupus erythematosus (SLE) patients. Materials & methods: 150 SLE patients and matched healthy controls were recruited. Polymorphisms were detected by PCR-RFLP and serum levels by ELISA. Results: Mean MMP-2 and TIMP-2 serum level and...

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Identifiers

PMID: 32969251
DOI: 10.2217/bmm-2020-0180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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