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PECAM-1 gene polymorphisms and soluble PECAM-1 level in rheumatoid arthritis and systemic lupus erythematosus patients: any link with clinical atherosclerotic events?

Clinical rheumatology - 1 Dec 2014

Pamuk Omer Nuri, Tozkir Hilmi, Uyanik Mehmet Sevki, Gurkan Hakan, Saritas Fatih, Duymaz Julide, Donmez Salim, Yazar Metin, Pamuk Gulsum Emel

Abstract excerpt

Genetic polymorphisms of platelet endothelial cell adhesion molecule-1 (PECAM-1) were found to play roles in atherosclerotic events. We determined PECAM-1 polymorphisms, soluble PECAM-1, and CD40L levels in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) and evaluated their associations with clinical atherosclerotic complications. We included 100 RA patients, 81 SLE patients, and 94 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25201689
DOI: 10.1007/s10067-014-2771-3

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