Article
The clinical significance of coagulation and the inflammatory response in autoimmunity.
Clinical reviews in allergy & immunology - 1 Apr 2012
Rubio-Jurado Benjamín, Iñiguez-Franco Paulina, Reyes Pedro A, Robles Gustavo, Salazar-Páramo Mario, Zavala-Cerna Guadalupe, Riebeling Carlos, Nava Arnulfo
Abstract excerpt
Maintenance of normal blood flow requires equilibrium between procoagulant and anticoagulant factors; occasionally, procoagulant activity predominates, leading to clot formation; frequently, tissue damage is the triggering factor. Hereditary factors, primary or acquired, play a role in the development of thrombosis. Primary thrombophilia is associated with hereditary factors, which promote hypercoagulability...
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