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Article

Regulation of neurocoel morphogenesis by Pard6 gamma b.

Developmental biology - 1 Dec 2008

Munson Chantilly, Huisken Jan, Bit-Avragim Nana, Kuo Taiyi, Dong P D, Ober Elke A, Verkade Heather, Abdelilah-Seyfried Salim, Stainier Didier Y R

Abstract excerpt

The Par3/Par6/aPKC protein complex plays a key role in the establishment and maintenance of apicobasal polarity, a cellular characteristic essential for tissue and organ morphogenesis, differentiation and homeostasis. During a forward genetic screen for liver and pancreas mutants, we identified a pard6gammab mutant, representing the first known pard6 mutant in a vertebrate organism. pard6gammab mutants exhibit...

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Identifiers

PMID: 18817769
DOI: 10.1016/j.ydbio.2008.08.033
PMCID: PMC2626139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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