Article
Kinase networks integrate profiles of N-methyl-D-aspartate receptor-mediated gene expression in hippocampus.
The Journal of biological chemistry - 5 Dec 2008
Coba Marcelo P, Valor Luis M, Kopanitsa Maksym V, Afinowi Nurudeen O, Grant Seth G N
Abstract excerpt
The postsynaptic N-methyl-d-aspartate (NMDA) receptor activates multiple kinases and changes the phosphorylation of many postsynaptic proteins organized in signaling networks. Because the NMDA receptor is known to regulate gene expression, it is important to examine whether networks of kinases control signaling to gene expression. We examined the requirement of multiple kinases and NMDA receptor-interacting...
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