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Structural and Functional Analysis of the Pore-Forming Toxin NetB from Clostridium perfringens

6 Feb 2013

Abstract excerpt

Clostridium perfringens is an anaerobic bacterium that causes numerous important human and animal diseases, primarily as a result of its ability to produce many different protein toxins. In chickens, C. perfringens causes necrotic enteritis, a disease of economic importance to the worldwide poultry industry. The secreted pore-forming toxin NetB is a key virulence factor in the pathogenesis of avian necrotic...

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PMID: 23386432
DOI: 10.1128/mbio.00019-13

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