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Article

Structural studies of receptor binding by cholera toxin mutants.

Protein science : a publication of the Protein Society - 1 Jul 1997

Merritt E A, Sarfaty S, Jobling M G, Chang T, Holmes R K, Hirst T R, Hol W G

Abstract excerpt

The wide range of receptor binding affinities reported to result from mutations at residue Gly 33 of the cholera toxin B-pentamer (CTB) has been most puzzling. For instance, introduction of an aspartate at this position abolishes receptor binding, whereas substitution by arginine retains receptor affinity despite the larger side chain. We now report the structure determination and 2.3-A refinement of the CTB...

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Source

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Identifiers

PMID: 9232653
DOI: 10.1002/pro.5560060716
PMCID: PMC2143749

Genes

LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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