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Article

A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese.

BMC cancer - 23 Sept 2008

Chen Huimei, Xu Lizhi, Qi Qiufeng, Yao Yanweng, Zhu Ming, Wang Yaping

Abstract excerpt

BACKGROUND: The human MutY homolog (hMYH), a DNA glycolsylase involved in the excision repair of oxidative DNA damage, is currently studied in colorectal cancer (CRC). We previously demonstrated a haplotype variant c.53C>T/c.74G>A of hMYH (T/A) increasing the risk for gastric cancer in Chinese. However, most investigations on correlation between hMYH and CRC are conducted in Western countries and the underlying...

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Identifiers

PMID: 18811933
DOI: 10.1186/1471-2407-8-269
PMCID: PMC2565682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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