Article
Characteristics of MUTYH variants in Japanese colorectal polyposis patients.
International journal of clinical oncology - 1 Jun 2018
Takao Misato, Yamaguchi Tatsuro, Eguchi Hidetaka, Tada Yuhki, Kohda Masakazu, Koizumi Koichi, Horiguchi Shin-Ichiro, Okazaki Yasushi, Ishida Hideyuki
Abstract excerpt
BACKGROUND: The base excision repair gene MUTYH is the causative gene of colorectal polyposis syndrome, which is an autosomal recessive disorder associated with a high risk of colorectal cancer. Since few studies have investigated the genotype-phenotype association in Japanese patients with MUTYH variants, the aim of this study was to clarify the clinicopathological findings in Japanese patients with MUTYH gene...
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