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MUTYH is a potential prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma

1 Dec 2022

Abstract excerpt

Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. The development of biomarkers for early detection and monitoring of HCC has not shown significant progress. Meanwhile, the second adenomatous polyposis-related gene, MUTYH, which encodes a DNA glycosylase, has been observed in its contribution to oxidative DNA damage repair. Abnormal expression of MUTYH can reduce...

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PMID: 39957908
DOI: 10.1016/j.livres.2022.12.002

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