Article
Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.
PloS one - 1 Jan 2017
Robiou-du-Pont Sébastien, Anand Sonia S, Morrison Katherine M, McDonald Sarah D, Atkinson Stephanie A, Teo Koon K, Meyre David
Abstract excerpt
Previous genome wide association studies (GWAS) identified associations of multiple common variants with diastolic and systolic blood pressure traits in adults. However, the contribution of these loci to variations of blood pressure in early life is unclear. We assessed the child and parental contributions of 33 GWAS single-nucleotide polymorphisms (SNPs) for blood pressure in 1,525 participants (515 children,...
Topics
- Adult
- Blood Pressure
- CSK Tyrosine-Protein Kinase
- Child, Preschool
- Female
- Genetic Markers
- Genome-Wide Association Study
- Humans
- Hypertension
- Infant
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Single Nucleotide