Article
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings.
Trends in genetics : TIG - 1 Nov 2008
McVey Mitch, Lee Sang Eun
Abstract excerpt
DNA double-strand breaks are normal consequences of cell division and differentiation and must be repaired faithfully to maintain genome stability. Two mechanistically distinct pathways are known to efficiently repair double-strand breaks: homologous recombination and Ku-dependent non-homologous end joining. Recently, a third, less characterized repair mechanism, named microhomology-mediated end joining (MMEJ),...
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