Article
Magnetic resonance imaging traits in siblings discordant for Alzheimer disease.
Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jul 2008
Cuenco Karen T, Green Robert C, Zhang J, Lunetta Kathryn, Erlich Porat M, Cupples L Adrienne, Farrer Lindsay A, DeCarli Charles
Abstract excerpt
BACKGROUND: Magnetic resonance imaging (MRI) can aid clinical assessment of brain changes potentially correlated with Alzheimer disease (AD). MRI traits may improve our ability to identify genes associated with AD-outcomes. We evaluated semi-quantitative MRI measures as endophenotypes for genetic studies by assessing their association with AD in families from the Multi-Institutional Research in Alzheimer Genetic...
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