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Article

BRCA1 is regulated by Chk2 in response to spindle damage.

Biochimica et biophysica acta - 1 Dec 2008

Chabalier-Taste Corinne, Racca Carine, Dozier Christine, Larminat Florence

Abstract excerpt

Inherited mutations of the breast cancer susceptibility gene 1 (BRCA1) confer an increased risk for breast, ovarian and prostate cancer. BRCA1 has been involved in regulation of cell cycle progression, DNA damage signaling and repair, maintenance of genome integrity, ubiquitination and regulation of transcription. Aside from its essential functions in the DNA damage response BRCA1 has been also involved in the...

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Source

Identifiers

PMID: 18804494
DOI: 10.1016/j.bbamcr.2008.08.006

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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