Article
[Drug resistance of multibacillary leprosy patients in Japan--results of molecular genetic analyses].
Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association - 1 Sept 2008
Ozaki Motoaki
Abstract excerpt
UNLABELLED: Gene mutation of Mycobacterium leprae was studied on bacilli-positive multibacillary leprosy patients since 2000 in Japan. SUBJECTS: LL 31 cases, BL 7 cases. RESULTS: gene mutation of folP was found in 19/36 cases (52.8%), that of rpoB in 13/33 cases (39.4%), that of gyrA in 6/31 cases (16.8%). Five cases showed both mutations of folP and rpoB, and one case showed those of fol/P and gyrA. Mutations of...
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