Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of gene mutations related with drug resistance in<i>Mycobacterium leprae</i>from leprosy patients using Touch-Down (TD) PCR

30 Apr 2003

Abstract excerpt

The lack of methods to identify Mycobacterium leprae with the resistance against multi-drugs quickly and specifically has hindered effective chemotherapy against M. leprae infection. To screen M. leprae with resistance against multi-drugs, the Touch-Down (TD)-PCR has been used in this study. Sequences of the folP, rpoA, B, and gyrA, B genes were analyzed for isolates of M. leprae from leprosy patients in Korea....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leprosy Research and Treatment
Share to Mycobacterium research and diagnosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12727362
DOI: 10.1016/s0928-8244(03)00038-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of gene mutations related with drug resistance in<i>Mycobacterium leprae</i>from leprosy patients using Touch-Down (TD) PCRPMID 12727362Read ↗

Mutations in genes related to drug resistance in Mycobacterium leprae isolates from leprosy patients in Korea.Semantic proximity Read ↗

Multidrug Resistant <i>Mycobacterium leprae</i> from Patients with LeprosySemantic proximity Read ↗

[Drug resistance of multibacillary leprosy patients in Japan--results of molecular genetic analyses].Semantic proximity Read ↗

Simultaneous Determination of Mycobacterium leprae Drug Resistance and Single-Nucleotide Polymorphism Genotype by Use of Nested Multiplex PCR with Amplicon Sequencing.Semantic proximity Read ↗

Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15.Semantic proximity Read ↗

Drug resistance in Mycobacterium leprae from patients with leprosy in China.Semantic proximity Read ↗

Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Nested PCR and the TaqMan SNP Genotyping Assay enhanced the sensitivity of drug resistance testing of Mycobacterium leprae using clinical specimens of leprosy patients.Semantic proximity Read ↗

Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.Semantic proximity Read ↗

[Multi-drug resistant Mycobacterium leprae from patients with leprosy].Semantic proximity Read ↗

<i>Mycobacterium leprae</i> and Leprosy: A CompendiumSemantic proximity Read ↗

Resistance to anti-leprosy drugs in multi-bacillary leprosy patients: The need for transformative action.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.