Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance to anti-leprosy drugs in multi-bacillary leprosy patients: The need for transformative action.

Indian journal of dermatology, venereology and leprology - 1 Jan 2026

Jindal Rashmi, Singh Itu, Goyal Dikshita, Mittal Arnav, Saini Anuj, Dhoundiyal Ritu, Sharma Rahul, Bisht Yashwant Singh, Roy Samarjit, Hemdani Ruchi

Abstract excerpt

Background Leprosy, caused by Mycobacterium leprae, remains a significant public health challenge, particularly in endemic regions. While multidrug therapy (MDT) has been effective, the emergence of antimicrobial resistance (AMR) to key drugs such as rifampicin, dapsone, and ofloxacin threatens leprosy control programs. Resistance mechanisms include mutations in genes such as rpoB (rifampicin), folP1 (dapsone),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dapsone

Share to Drug Resistance, Bacterial

Share to Mycobacterium leprae

Share to Ofloxacin

Share to Rifampin

Share to Young Adult

Source

Identifiers

PMID: 41518316
DOI: 10.25259/IJDVL_1842_2024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance to anti-leprosy drugs in multi-bacillary leprosy patients: The need for transformative action.PMID 41518316Read ↗

Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15.Semantic proximity Read ↗

Molecular Surveillance of Antimicrobial Resistance of Mycobacterium leprae from Leprosy Patients in Zhejiang Province, ChinaSemantic proximity Read ↗

Epidemiology of first-and second-line anti-tuberculosis drug resistance in new pulmonary tuberculosis cases in Addis Ababa metropolitan area, EthiopiaSemantic proximity Read ↗

Multidrug-resistant tuberculosis: a comprehensive review of pathogenesis, drug resistance, current treatment and future prospects.Semantic proximity Read ↗

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium lepraeSemantic proximity Read ↗

Drug-Resistant Tuberculosis 2020: Where We StandSemantic proximity Read ↗

Optimizing treatment of lepromatous form of leprosy using ofloxacin on top of standard multi-drug therapy in National Referral Hospital, Jakarta, IndonesiaSemantic proximity Read ↗

Optimizing treatment of lepromatous form of leprosy using ofloxacin on top of standard multi-drug therapy in National Referral Hospital, Jakarta, IndonesiaSemantic proximity Read ↗

Evidence for Mycobacterium leprae Drug Resistance in a Large Cohort of Leprous Neuropathy Patients from India.Semantic proximity Read ↗

Leprosy Drug Resistance Surveillance in Colombia: The Experience of a Sentinel Country.Semantic proximity Read ↗

Emergence of bedaquiline-resistant tuberculosis and of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains with rpoB Ile491Phe mutation not detected by Xpert MTB/RIF in Mozambique: a retrospective observational study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.