Article
Mutations in genes related to drug resistance in Mycobacterium leprae isolates from leprosy patients in Korea.
The Journal of infection - 1 Jan 2005
You Eun-Young, Kang Tae Jin, Kim Se-Kon, Lee Seong-Beom, Chae Gue-Tae
Abstract excerpt
OBJECTIVE: Identification of the presence and drug resistance of Mycobacterium leprae is key to the diagnosis and treatment of leprosy in non-endemic country like Korea. The aim of this study was to screen the drug target DNA such as folP, rpoB, gyr, and 23S rRNA of drug resistance strain of M. leprae. PATIENTS AND METHODS: Sequences of those genes were analyzed for the 104 bacterial index positive cases out of...
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