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Article

Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome.

Psychiatric genetics - 1 Oct 2008

Crowley James J, Lipsky Robert H, Lucki Irwin, Berrettini Wade H

Abstract excerpt

The identification of genetic variants regulating antidepressant response would allow for more individualized, rational, and successful drug treatments. We previously identified a region of mouse chromosome 19 that strongly influences citalopram response in an antidepressant model, the tail suspension test. By virtue of their location in this loci, expression in brain, and involvement in monoamine...

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Identifiers

PMID: 18797399
DOI: 10.1097/YPG.0b013e3283052ff7

Genes

ADRB1

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