Article
Response-guided treatment of cirrhotic chronic hepatitis B patients: multicenter prospective study.
World journal of gastroenterology - 14 Jan 2015
Gu Er-Li, Yu Yi-Qi, Wang Jia-Li, Ji Yan-Yan, Ma Xiu-Yun, Xie Qing, Pan Hong-Ying, Wu Shan-Min, Li Jun, Chen Cheng-Wei, Xu Xiao-Wei, Wang Yue-Er, Yao Guang-Bi, Wang Hong, Zhang Wen-Hong
Abstract excerpt
AIM: To observe the effect of response-guided add-on therapy with adefovir (ADV) and lamivudine (LAM) in cirrhotic hepatitis B (CHB) patients. METHODS: A total of 100 patients with CHB and cirrhosis were divided into three arms according to hepatitis B virus (HBV) DNA level after 24 wk LAM monotherapy: Arm A (complete response, HBV DNA ≤ 60 IU/mL, n = 49), Arm B (partial response, HBV DNA: 60-2000 IU/mL, n = 31)...
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