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Article

Class I PI3K in oncogenic cellular transformation.

Oncogene - 18 Sept 2008

Zhao L, Vogt P K

Abstract excerpt

Class I phosphoinositide 3-kinase (PI3K) is a dimeric enzyme, consisting of a catalytic and a regulatory subunit. The catalytic subunit occurs in four isoforms designated as p110 alpha, p110 beta, p110 gamma and p110 delta. These isoforms combine with several regulatory subunits; for p110 alpha, beta and delta, the standard regulatory subunit is p85, for p110 gamma, it is p101. PI3Ks play important roles in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18794883
DOI: 10.1038/onc.2008.244
PMCID: PMC2757120

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