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Article

Oncogenic signaling of class I PI3K isoforms.

Oncogene - 17 Apr 2008

Denley A, Kang S, Karst U, Vogt P K

Abstract excerpt

The catalytic subunits of class I PI3Ks comprise four isoforms: p110alpha, p110beta, p110delta and p110gamma. Cancer-specific gain-of-function mutations in p110alpha have been identified in various malignancies. Cancer-specific mutations in the non-alpha isoforms of class I PI3K have not yet been...

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Identifiers

PMID: 17998941
DOI: 10.1038/sj.onc.1210918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17998941-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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