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Article

The 22G>A polymorphism in the adenosine deaminase gene impairs catalytic function but does not affect reactive hyperaemia in humans in vivo.

Pharmacogenetics and genomics - 1 Oct 2008

Riksen Niels P, Franke Barbara, van den Broek Petra, Naber Marlies, Smits Paul, Rongen Gerard A

Abstract excerpt

OBJECTIVES: During ischaemia, the extracellular concentration of the endogenous nucleoside adenosine increases rapidly. Subsequent adenosine receptor stimulation induces various effects, including vasodilation, which can protect the tissue against the ischaemic insult. Adenosine deaminase (ADA) i...

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Identifiers

PMID: 18794722
DOI: 10.1097/FPC.0b013e328305e630

Genes

ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18794722-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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