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Article

ADA*2 allele of the adenosine deaminase gene may protect against coronary artery disease.

Cardiology - 1 Jan 2007

Safranow Krzysztof, Rzeuski Ryszard, Binczak-Kuleta Agnieszka, Czyzycka Edyta, Skowronek Janusz, Jakubowska Katarzyna, Wojtarowicz Andrzej, Loniewska Beata, Ciechanowicz Andrzej, Kornacewicz-Jach Zdzislawa, Chlubek Dariusz

Abstract excerpt

BACKGROUND/AIMS: The common G22A polymorphism in the adenosine deaminase (ADA) gene leads to substitution Asp8Asn. The lower activity of the enzyme encoded by A22 (ADA*2) allele may increase tissue concentrations of adenosine, a potent cardioprotective agent. In a case-control study, we investigated the association between ADA polymorphism and coronary artery disease (CAD). METHODS: A hundred and seventy-one CAD...

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Source

Identifiers

PMID: 17287605
DOI: 10.1159/000099096

Genes

ADA
CAD
ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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