Article
The 1976C>T polymorphism in the adenosine A2A receptor gene does not affect the vasodilator response to adenosine in humans in vivo.
Pharmacogenetics and genomics - 1 Jul 2007
Riksen Niels P, Franke Barbara, van den Broek Petra, Smits Paul, Rongen Gerard A
Abstract excerpt
The 1976C>T polymorphism in the adenosine A2A receptor gene (ADORA2A) modulates the psychological response to administration of the adenosine receptor antagonist caffeine. We quantified the vascular response to adenosine and caffeine to determine the relevance of this variant allele in the physiological response to these agents. We selected 10 study participants with the TT genotype and 10 CC controls, matched...
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