Article
Gender-specific association of ADA genetic polymorphism with human longevity.
Biogerontology - 1 Aug 2010
Napolioni Valerio, Lucarini Nazzareno
Abstract excerpt
Aim of this study was to investigate whether the polymorphic ADA (Adenosine Deaminase, EC 3.5.4.4) gene, which determines the cellular level of adenosine and plays a crucial role in the regulation of the immune system and in the control of metabolic rates, is involved in longevity. 884 unrelated healthy individuals (age range 10-106 years, 400 males and 484 females) from central Italy were studied. ADA genotyping...
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