Article

Augmented hyperemia and reduced tissue injury in response to ischemia in subjects with the 34C > T variant of the AMPD1 gene

2007-04-01

Abstract excerpt

<h4>Introduction:</h4> In patients with cardiovascular disease the 34C > T variant of the adenosine monophosphate deaminase (AMPD1) gene is associated with improved survival. We hypothesized that this variant results in enhanced intracellular formation of adenosine during ischemia, thereby increasing hyperemia and reducing tissue injury in response to ischemia. As increased intracellular adenosine formation would...

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Identifiers and source

Literature Corpus work: e264313f-77c9-5df7-b625-f949306029b5
DOI: 10.1111/j.1365-2125.2007.02886_6.x
PMCID: PMC2203232

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