Article
Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene.
Acta cardiologica - 1 Feb 2014
Saccucci Patrizia, Binczak-Kuleta Agnieszka, Banci Maria, Krzysztalowska Maja, Dofcaci Alessandro, Safranow Krzysztof, Magrini Andrea, Loniewska Beata, Kornacewicz-Jach Zdzislawa, Chlubek Dariusz, Bottini Egidio, Ciechanowicz Andrzej, Gloria-Bottini Fulvia
Abstract excerpt
OBJECTIVES: The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary artery disease (CAD) prompted us to study the possible relevance of three intragenic...
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